Year : 2016 | Volume
: 9 | Issue : 1 | Page : 18--22
Prevention of reperfusion tachyarrhythmia after CABG: magnesium versus lidocaine
Magdy M Atallah
Cardiothoracic Anesthesia Unit, Department of Anesthesia & SIC, Mansoura Faculty of Medicine, Mansoura, Egypt
Reperfusion tachyarrhythmia after aortic cross-clamp (ACC) release is one of the most commonly encountered complications after coronary artery bypass grafting (CABG) surgery, and its control may save these patients.
Materials and methods
Ninety patients who had undergone CABG surgery were enrolled in this study. Patients were assigned randomly to three groups (30 patients each). The lidocaine group (LIDO) group received lidocaine (2 mg/kg) in 100 ml isotonic saline, the magnesium group (MAGN) group received magnesium (30 mg/kg) diluted in 100 ml of an isotonic saline 0.9% solution, and the control group received 100 ml normal saline by a pump circuit 3-5 min before ACC release. Anesthetic management, weaning protocol from cardiopulmonary bypass, was standardized. All the patients were monitored after the release of ACC and electrical rhythms (including ventricular fibrillation and supraventricular tachyarrhythmia) were recorded.
Incidences of postrelease of ACC and ventricular fibrillation were lower in the lidocaine and magnesium groups compared with the control group [7 (23%), 4 (13%) vs. 11 (36%)] (P = 0.042). Also, the incidence of an atrioventricular block postrelease ACC was higher in the lidocaine group compared with the magnesium and control groups [7 (23%) vs. 2 (6%) and 3 (10%), respectively] (P = 0.039). The need for a temporary pace maker was higher in the lidocaine group compared with the magnesium and control groups [7 (23%) vs. 2 (6%) and 1 (3%), respectively] (P = 0.044). Also, the total duration of ICU stay was shorter in the magnesium group compared with the lidocaine and control groups.
The administration of lidocaine and magnesium sulfate before the release of ACC reduced the incidence of ventricular fibrillation. The administration of magnesium shortened the ICU stay in adult patients undergoing CABG surgery by cardiopulmonary bypass. However, the administration of Lidocaine was associated with more transient atrioventricular block.
Magdy M Atallah
Cardiothoracic Anesthesia Unit, Department of Anesthesia & SIC, Mansoura Faculty of Medicine, Mansoura
|How to cite this article:|
Atallah MM. Prevention of reperfusion tachyarrhythmia after CABG: magnesium versus lidocaine.Ain-Shams J Anaesthesiol 2016;9:18-22
|How to cite this URL:|
Atallah MM. Prevention of reperfusion tachyarrhythmia after CABG: magnesium versus lidocaine. Ain-Shams J Anaesthesiol [serial online] 2016 [cited 2022 May 26 ];9:18-22
Available from: http://www.asja.eg.net/article.asp?issn=1687-7934;year=2016;volume=9;issue=1;spage=18;epage=22;aulast=Atallah;type=0